4ksc » P-glycoprotein, inward-facing conformation 2b
- Type: Transmembrane (3 classes)
- Class: Alpha-helical polytopic (156 superfamilies)
- Superfamily: ABC transporters (27 families) 3.A.1 (TCDB)
- Family: Multidrug resistance exporter (MDR) (66 proteins) 3.A.1.201 (TCDB) IPR039421
- Species: Mus musculus (411 proteins)
- Localization: Eukaryotic plasma membrane (3316 proteins)
| 4ksc >> P-glycoprotein, inward-facing conformation 2b | |
|---|---|
| Hydrophobic Thickness or Depth | 30.0 Å |
| Tilt Angle | 4° |
| ΔGtransfer | -89.2 kcal/mol |
| Links to 4ksc | PDB Sum, PDB, MSD, MMDB, Encompass |
| Topology | subunit A (N terminus cytoplasmic side) |
| Resolution | 4.0 |
| Primary PDB represention | 4ksc |
| Other PDB entries representing this structure | 4q9h (3.4), 4q9k (3.8) |
| Number of TM secondary structures | 12 |
| Membranome |  |
| Uniprot | MDR1A_MOUSE |
| Subunits: 1 | |||
|---|---|---|---|
| A - Tilt: 4 - TM segments: 1( 45- 71), 2( 113- 132), 3( 183- 207), 4( 209- 228), 5( 288- 310), 6( 327- 348), 7( 708- 729), 8( 751- 775), 9( 825- 847),10( 852- 874),11( 931- 953),12( 970- 991) | |||