5u74 » Niemann-Pick C1 protein, NPC1, structure 2
- Type: Transmembrane (3 classes)
- Class: Alpha-helical polytopic (156 superfamilies)
- Superfamily: Resistance-nodulation-cell division (5 families) 2.A.6 (TCDB) CL0322
- Family: Patched family (40 proteins) 2.A.6.6 (TCDB) PF02460 IPR003392 PDBsum
- Species: Homo sapiens (2659 proteins)
- Localization: Lysosome membrane (102 proteins)
| 5u74 >> Niemann-Pick C1 protein, NPC1, structure 2 | |
|---|---|
| Hydrophobic Thickness or Depth | 31.0 Å |
| Tilt Angle | 5° |
| ΔGtransfer | -84.3 kcal/mol |
| Links to 5u74 | PDB Sum, PDB, MSD, MMDB, Encompass |
| Topology | subunit A (N terminus cytoplasmic side) |
| Resolution | 3.34 |
| Primary PDB represention | 5u74 |
| Other PDB entries representing this structure | none |
| Number of TM secondary structures | 12 |
| Membranome |  |
| Uniprot | NPC1_HUMAN |
| Subunits: 1 | |||
|---|---|---|---|
| A - Tilt: 5 - TM segments: 1( 351- 369), 2( 621- 638), 3( 654- 678), 4( 686- 707), 5( 731- 751), 6( 759- 783), 7( 834- 854), 8(1098-1117), 9(1121-1145),10(1153-1173),11(1194-1214),12(1225-1248) | |||