6cnj » Nicotinic acetylcholine receptor, alpha-4/beta-2, structure 2
- Type: Transmembrane (3 classes)
- Class: Alpha-helical polytopic (156 superfamilies)
- Superfamily: Pentameric ligand-gated ion channels (2 families) 1.A.9 (TCDB) PF02932
- Family: Ligand-gated ion channel of neurotransmitter receptors (126 proteins) 1.A.9 (TCDB) PF02932 IPR008132 PDBsum
- Species: Homo sapiens (2659 proteins)
- Localization: Eukaryotic plasma membrane (3316 proteins)
| 6cnj >> Nicotinic acetylcholine receptor, alpha-4/beta-2, structure 2 | |
|---|---|
| Hydrophobic Thickness or Depth | 31.0 Å |
| Tilt Angle | 0° |
| ΔGtransfer | -128.8 kcal/mol |
| Links to 6cnj | PDB Sum, PDB, MSD, MMDB, Encompass |
| Topology | subunit A (N terminus extracellular side) |
| Resolution | 3.7 EM |
| Primary PDB represention | 6cnj |
| Other PDB entries representing this structure | 6cnk (3.9 EM) |
| Number of TM secondary structures | 20 |
| Membranome |  |
| Uniprot | ACHA4_HUMAN, ACHB2_HUMAN |
| Subunits: 5 | |||
|---|---|---|---|
| A - Tilt: 15 - TM segments: 1( 221- 242), 2( 248- 264), 3( 279- 303), 4( 358- 379) | |||
| B - Tilt: 16 - TM segments: 1( 213- 234), 2( 240- 256), 3( 271- 295), 4( 349- 367) | |||
| C - Tilt: 15 - TM segments: 1( 213- 234), 2( 240- 256), 3( 271- 295), 4( 349- 367) | |||
| D - Tilt: 15 - TM segments: 1( 221- 242), 2( 248- 264), 3( 279- 303), 4( 358- 379) | |||
| E - Tilt: 16 - TM segments: 1( 213- 234), 2( 240- 256), 3( 271- 295), 4( 349- 367) | |||