7d99 » Potassium-chloride co-transporter KCC4 (SLC12A7)
- Type: Transmembrane (3 classes)
- Class: Alpha-helical polytopic (156 superfamilies)
- Superfamily: APC (Amino acid-Polyamine-organoCation) superfamily (14 families) CL0062
- Family: Cation-chloride cotransporter (37 proteins) 2.A.30 (TCDB) PF03522 IPR018491 PDBsum
- Species: Homo sapiens (2659 proteins)
- Localization: Eukaryotic plasma membrane (3316 proteins)
| 7d99 >> Potassium-chloride co-transporter KCC4 (SLC12A7) | |
|---|---|
| Hydrophobic Thickness or Depth | 32.0 Å |
| Tilt Angle | 0° |
| Radius of curvature | 100 Å |
| ΔGtransfer | -137.2 kcal/mol |
| Links to 7d99 | PDB Sum, PDB, MSD, MMDB, Encompass |
| Topology | subunit A (N terminus cytoplasmic side) |
| Resolution | 2.9 EM |
| Primary PDB represention | 7d99 |
| Other PDB entries representing this structure | none |
| Number of TM secondary structures | 24 |
| Membranome |  |
| Uniprot | S12A7_HUMAN |
| Subunits: 2 | |||
|---|---|---|---|
| A - Tilt: 9 - TM segments: 1( 120- 142), 2( 150- 172), 3( 197- 225), 4( 250- 270), 5( 272- 300), 6( 420- 440), 7( 451- 473), 8( 505- 531), 9( 555- 571),10( 574- 598),11( 613- 632),12( 636- 651) | |||
| B - Tilt: 9 - TM segments: 1( 120- 142), 2( 150- 172), 3( 197- 225), 4( 250- 270), 5( 272- 300), 6( 420- 440), 7( 451- 473), 8( 505- 531), 9( 555- 571),10( 574- 598),11( 613- 632),12( 636- 651) | |||