6qfa » GABA-beta3 homopentamer with histamine and megabody
- Type: Transmembrane (3 classes)
- Class: Alpha-helical polytopic (156 superfamilies)
- Superfamily: Pentameric ligand-gated ion channels (2 families) 1.A.9 (TCDB) PF02932
- Family: Ligand-gated ion channel of neurotransmitter receptors (126 proteins) 1.A.9 (TCDB) PF02932 IPR008132 PDBsum
- Species: Homo sapiens (2659 proteins)
- Localization: Eukaryotic plasma membrane (3316 proteins)
| 6qfa >> GABA-beta3 homopentamer with histamine and megabody | |
|---|---|
| Hydrophobic Thickness or Depth | 31.2 Å |
| Tilt Angle | 0° |
| ΔGtransfer | -142.7 kcal/mol |
| Links to 6qfa | PDB Sum, PDB, MSD, MMDB, Encompass |
| Topology | subunit B (N terminus extracellular side) |
| Resolution | 2.49 EM |
| Primary PDB represention | 6qfa |
| Other PDB entries representing this structure | 7qn6 (2.9 EM), 7qn8 (3.1 EM), 7qnd (3.4 EM) |
| Number of TM secondary structures | 20 |
| Membranome |  |
| Uniprot | B5Z8H1_HELPG, GBRB3_HUMAN |
| Subunits: 5 | |||
|---|---|---|---|
| A - Tilt: 11 - TM segments: 1( 222- 242), 2( 247- 269), 3( 280- 301), 4( 426- 445) | |||
| B - Tilt: 11 - TM segments: 1( 222- 242), 2( 247- 269), 3( 280- 301), 4( 426- 445) | |||
| C - Tilt: 11 - TM segments: 1( 222- 242), 2( 247- 269), 3( 280- 301), 4( 426- 445) | |||
| D - Tilt: 11 - TM segments: 1( 222- 242), 2( 247- 269), 3( 280- 301), 4( 426- 445) | |||
| E - Tilt: 11 - TM segments: 1( 222- 242), 2( 247- 269), 3( 280- 301), 4( 426- 445) | |||