2dyr » Mitochondrial cytochrome c oxidase
2dyr >> Mitochondrial cytochrome c oxidase
Hydrophobic Thickness or Depth28.0 Å
Tilt Angle0°
ΔGtransfer-198.1 kcal/mol
Links to 2dyrPDB Sum, PDB, MSD, MMDB, Encompass
Topologysubunit A (N terminus mitochondrial matrix)
Resolution1.8
Primary PDB represention2dyr
Other PDB entries representing this structure1occ (2.8), 1oco (2.8), 1ocr (2.35), 1ocz (2.9), 1v54 (1.8), 1v55 (1.9), 2dys (2.2), 2eij (1.9), 2eik (2.1), 2eil (2.1), 2eim (2.6), 2ein (2.7), 2occ (2.3), 2y69 (1.95), 2zxw (2.5), 3abk (2.0), 3abl (2.1), 3abm (1.95), 3ag1 (2.2), 3ag2 (1.8), 3ag3 (1.8), 3ag4 (2.05), 3asn (3.0), 3aso (2.3), 3wg7 (1.9), 3x2q (2.0), 5b1a (1.5), 5b1b (1.6), 5b3s (1.68), 5w97 (2.3), 5wau (1.95), 5x19 (2.2), 5x1b (2.4), 5x1f (2.2), 5xdq (1.77), 5xdx (1.99), 5z84 (1.85), 5z85 (1.85), 5z86 (1.85), 5zco (1.9), 5zcp (1.65), 5zcq (1.65), 6j8m (1.9), 6juw (1.8), 6jy3 (1.85), 6jy4 (1.95), 6nkn (2.5), 6nmf (2.8), 6nmp (2.9), 7ev7 (1.7), 7xma (2.2), 7xmb (2.2), 8h8r (1.7), 8h8s (1.7), 8ijn (1.8)
Number of TM secondary structures56
Membranome
UniprotCOX1_BOVIN, COX2_BOVIN, COX3_BOVIN, COX41_BOVIN, COX5A_BOVIN, COX5B_BOVIN, COX6C_BOVIN, COX7B_BOVIN, COX7C_BOVIN, COX8B_BOVIN, CX6A2_BOVIN, CX6B1_BOVIN, CX7A1_BOVIN
Download OPM File: 2dyr.pdb
PDB Sum, PDB
Topology in Mitochondrial inner membrane
intermembrane space
mitochondrial matrix
3D view in GLMol | LiteMol | Jmol | iCn3D
Verification: Mitochondrial cytochrome c oxidase
Calculated hydrophobic thickness is about 1.5 Å… smaller than from experimental data (Montecucco et al. 1982).
Subunits: 20
A - Tilt: 8 - TM segments: 1( 18- 39), 2( 56- 78), 3( 99- 117), 4( 142- 162), 5( 186- 211), 6( 231- 255), 7( 271- 288), 8( 304- 325), 9( 336- 359),10( 372- 393),11( 409- 429),12( 452- 472)
B - Tilt: 11 - TM segments: 1(27-47),2(59-77)
C - Tilt: 4 - TM segments: 1( 17- 35), 2( 41- 55), 3( 82- 100), 4( 126- 146), 5( 161- 181), 6( 197- 217), 7( 237- 258)view assembly page
D - Tilt: 36 - TM segments: 1(78-99)
G - Tilt: 20 - TM segments: 1(16-37)
I - Tilt: 5 - TM segments: 1(16-36)
J - Tilt: 29 - TM segments: 1(34-54)
K - Tilt: 16 - TM segments: 1(14-33)
L - Tilt: 15 - TM segments: 1(22-43)
M - Tilt: 22 - TM segments: 1(15-36)
N - Tilt: 9 - TM segments: 1( 18- 39), 2( 56- 79), 3( 99- 117), 4( 142- 162), 5( 186- 211), 6( 233- 255), 7( 271- 288), 8( 304- 325), 9( 336- 359),10( 372- 394),11( 408- 429),12( 453- 472)
O - Tilt: 11 - TM segments: 1(27-47),2(59-77)
P - Tilt: 4 - TM segments: 1(17-35),2(40-54),3(82-100),4(126-145),5(162-181),6(197-217),7(237-258)
Q - Tilt: 37 - TM segments: 1(77-99)
T - Tilt: 21 - TM segments: 1(16-37)
V - Tilt: 4 - TM segments: 1(16-34)
W - Tilt: 28 - TM segments: 1(34-54)
X - Tilt: 17 - TM segments: 1(14-33)
Y - Tilt: 15 - TM segments: 1(22-42)
Z - Tilt: 23 - TM segments: 1(15-36)
References: 1
Montecucco C, Smith GA, Dabbeni-sala F, Johansson A, Galante YM, and Bisson R (1982) Bilayer thickness and enzymatic activity in the mitochondrial cytochrome c oxidase and ATPase complex. FEBS Lett. 144: 145-148. PubMed